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Clinical trial · no report yet · Phase 2
A022101 trial: what clinicians have said so far
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
- NCT05673148 ↗
- Recruiting
- Alliance for Clinical Trials in Oncology
- Focused size, estimated: 1–150 verified statements once built
We haven't built an HCP commentary report on A022101 (limited metastatic colorectal cancer; tests a strategy, not a drug) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on A022101 so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Indexed so far | |
|---|---|
| 4 posts on X, typically up to 18 once built |
The trial
ClinicalTrials.gov- Official title
- A Pragmatic Randomized Phase II Trial Evaluating Total Ablative Therapy for Patients With Limited Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery (ERASur)
- Phase
- Phase 2
- Status
- Recruiting
- Conditions
- Metastatic Colorectal Adenocarcinoma; Stage IV Colorectal Cancer AJCC v8; Oligometastatic Colorectal Carcinoma
- Interventions
- Stereotactic Ablative Radiotherapy; Resection; Microwave Ablation; Chemotherapy; Computed Tomography; Magnetic Resonance Imaging; Positron Emission Tomography
- Arms
- Arm 1 (TAT, SOC chemotherapy · Experimental
- Arm 2 (SOC chemotherapy) · Active comparator
- Enrollment
- 146 (estimated)
- Primary outcomes
- Overall Survival (OS)
- Sponsor
- Alliance for Clinical Trials in Oncology with National Cancer Institute (NCI)
- Start
- Oct 9, 2023
- Primary completion
- Jul 3, 2028 (estimated)
- Results posted
- No
- Registry record
- NCT05673148 · updated Nov 3, 2026
Publications
linked from the registry- Hitchcock KE, Miller ED, Shi Q, Dixon JG, Gholami S, White SB, Wu C, Goulet CC, George M, Jee KW, Wright CL, Yaeger R, Shergill A, Hong TS, George TJ, O'Reilly EM, Meyerhardt JA, Romesser PB. Alliance for clinical trials in Oncology (Alliance) trial A022101/NRG-GI009: a pragmatic randomized phase III trial evaluating total ablative therapy for patients with limited metastatic colorectal cancer: evaluating radiation, ablation, and surgery (ERASur). BMC Cancer. 2024 Feb 13;24(1):201. doi: 10.1186/s12885-024-11899-2. PubMed 38350888
- Miller ED, Hitchcock KE, Romesser PB. Oligometastatic Colorectal Cancer: A Review of Definitions and Patient Selection for Local Therapies. J Gastrointest Cancer. 2023 Dec;54(4):1116-1127. doi: 10.1007/s12029-022-00900-5. Epub 2023 Jan 18. PubMed 36652155