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Clinical trial · no report yet · Phase 3

ADAURA2

A Global Study to Assess the Effects of Osimertinib in Participants With EGFRm Stage IA2-IA3 NSCLC Following Complete Tumour Resection

  • NCT05120349 ↗
  • Active not recruiting
  • AstraZeneca
  • 27 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube13
Podcasts10
X threads4

The trial

ClinicalTrials.gov
Official title
A Phase III, Double-blind, Randomised, Placebo-Controlled, International Study to Assess the Efficacy and Safety of Adjuvant Osimertinib Versus Placebo in Participants With EGFR Mutation-positive Stage IA2-IA3 Non-small Cell Lung Cancer, Following Complete Tumour Resection
Phase
Phase 3
Status
Active not recruiting
Conditions
Non-Small Cell Lung Cancer
Interventions
Osimertinib; Placebo
Arms
  • Osimertinib · Experimental
  • Placebo · Placebo comparator
Enrollment
390
Primary outcomes
  • Disease-Free Survival (DFS) in high-risk stratum
Sponsor
AstraZeneca
Start
Feb 21, 2022
Primary completion
Aug 2, 2027 (estimated)
Results posted
No
Registry record
NCT05120349 · updated Jul 6, 2026

Publications

linked from the registry
  • Murat-Onana ML, Ramalingam SS, Janne PA, Gray JE, Ahn MJ, John T, Yatabe Y, Huang X, Rukazenkov Y, Javey M, Brown H, Li-Sucholeiki X. EGFR mutation testing across the osimertinib clinical program. Lung Cancer. 2025 Jun;204:108549. doi: 10.1016/j.lungcan.2025.108549. Epub 2025 Apr 18. PubMed 40311309