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Clinical trial · no report yet · Phase 2

ADEPPT

Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads2
Bluesky threads1

The trial

ClinicalTrials.gov
Official title
A Multicentre, Single-arm Phase II Trial of Adagrasib in Patients With KRASG12C-mutant NSCLC, Including the Elderly (≥70 Years) or Patients With Poor Performance Status
Phase
Phase 2
Status
Active, not recruiting
Conditions
NSCLC Stage IV; KRAS P.G12C
Interventions
Adagrasib
Arms
  • Treatment Arm · Experimental
Enrollment
68 (estimated)
Primary outcomes
  • Objective Response Rate (ORR) per RECIST v1.1, assessed at 12 weeks.
Sponsor
ETOP IBCSG Partners Foundation with Mirati Therapeutics Inc.
Start
Jun 12, 2023
Primary completion
Jul 28, 2025
Results posted
No
Registry record
NCT05673187 · updated Sep 3, 2026