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Clinical trial · no report yet · Phase 1/Phase 2

Agni-01

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

  • NCT06060613 ↗
  • Recruiting
  • Obsidian Therapeutics, Inc.
  • 17 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube8
Podcasts6
X threads3

The trial

ClinicalTrials.gov
Official title
A Phase 1/2, Open-Label Study to Investigate the Safety and Efficacy of Membrane Bound IL15 Expressing Tumor-Infiltrating Lymphocytes (OBX-115) In Participants With Advanced Solid Tumors
Phase
Phase 1/Phase 2
Status
Recruiting
Conditions
Tumor Skin; Metastatic Melanoma; Melanoma; Lung Cancer; Metastatic Lung Cancer; Non Small Cell Lung Cancer; Metastatic Non Small Cell Lung Cancer
Interventions
OBX-115
Arms
  • Participants with advanced solid tumors · Experimental
Enrollment
254 (estimated)
Primary outcomes
  • Incidence and nature of dose-limiting toxicities (DLTs)
  • The proportion of participants who have a confirmed complete response (CR) or partial response (PR) per RECIST v1.1
  • The proportion of participants who have a confirmed complete response (CR) or partial response (PR) per RECIST v1.1
Sponsor
Obsidian Therapeutics, Inc.
Start
Oct 25, 2023
Primary completion
Jun 30, 2029 (estimated)
Results posted
No
Registry record
NCT06060613 · updated Oct 5, 2026