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Clinical trial · no report yet · Phase 2

DARE

DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
YouTube20
Podcasts11
X threads9
Bluesky threads4

The trial

ClinicalTrials.gov
Official title
A Randomized, Phase II Trial of Circulating Tumor DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)
Phase
Phase 2
Status
Active, not recruiting
Conditions
Breast Cancer
Interventions
Palbociclib; Fulvestrant; Adjuvant Therapy
Arms
  • Arm A · Experimental
  • Arm B · Active comparator
Enrollment
70 (estimated)
Primary outcomes
  • Surveillance/ctDNA screening Phase
  • Therapeutic Phase
Sponsor
Criterium, Inc.
Start
Feb 9, 2021
Primary completion
Dec 31, 2027 (estimated)
Results posted
No
Registry record
NCT04567420 · updated Oct 15, 2026