Clinical trial · no report yet · Phase 3
HA-PCI
Hippocampus Avoidance PCI vs PCI
- NCT01780675 ↗
- Completed
- The Netherlands Cancer Institute
- 3 commentary sources found
- Focused
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Commentary we found
Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built. Commentary is thin so far, so the report would be short.
| Channel | Found | |
|---|---|---|
| X threads | 3 |
The trial
ClinicalTrials.gov- Official title
- Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance in SCLC a Randomized Phase III Trial
- Phase
- Phase 3
- Status
- Completed
- Conditions
- Small Cell Lung Cancer; Lung Cancer
- Interventions
- Radiation Prophylactic Cranial Irradiation; Radiation Hippocampal Avoidance PCI
- Arms
- Prophylactic Cranial Irradiation · Active comparator
- Hippocampal Avoidance PCI · Experimental
- Enrollment
- 168
- Primary outcomes
- neurocognitive decline
- Sponsor
- The Netherlands Cancer Institute with Dutch Cancer Society
- Start
- Apr 2013
- Primary completion
- Apr 1, 2019
- Results posted
- No
- Registry record
- NCT01780675 · updated Jan 21, 2022
Publications
linked from the registry- Zeng H, Schagen SB, Hendriks LEL, Sanchez-Benavides G, Jaspers JPM, Manero RM, Lievens Y, Murcia-Mejia M, Kuenen M, Rico-Oses M, Albers EAC, Samper P, Houben R, de Ruiter MB, Dieleman EMT, Lopez-Guerra JL, De Jaeger K, Counago F, Lambrecht M, Calvo-Crespo P, Belderbos JSA, De Ruysscher DKM, Rodriguez de Dios N. Impact of HA-PCI on self-reported cognitive functioning and brain metastases in small-cell lung cancer: Pooled findings of NCT01780675 and PREMER trials. Lung Cancer. 2025 Jan;199:108036. doi: 10.1016/j.lungcan.2024.108036. Epub 2024 Nov 23. PubMed 39615412
- Ishibashi A, Kurosaki H, Miura K, Utsumi N, Sakurai H. Influence of Modulation Factor on Treatment Plan Quality and Irradiation Time in Hippocampus-Sparing Whole-Brain Radiotherapy Using Tomotherapy. Technol Cancer Res Treat. 2021 Jan-Dec;20:15330338211045497. doi: 10.1177/15330338211045497. PubMed 34632876