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Clinical trial · no report yet · Phase 2
MR-ADAPTOR trial: what clinicians have said so far
Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer
- NCT03224000 ↗
- Active, not recruiting
- M.D. Anderson Cancer Center
- Focused size, estimated: 1–150 verified statements
We haven't built an HCP commentary report on MR-ADAPTOR (HPV+ oropharyngeal squamous cell carcinoma; tests a strategy, not a drug) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on MR-ADAPTOR so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Indexed so far | |
|---|---|
| 3 posts on X |
The trial
ClinicalTrials.gov- Official title
- Bayesian Phase II Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer
- Phase
- Phase 2
- Status
- Active, not recruiting
- Conditions
- Malignant Neoplasms of Lip Oral Cavity and Pharynx; Oropharyngeal Cancer
- Interventions
- Modified Barium Swallow (MBS); Swallowing Questionnaire; Symptom Questionnaire; Video-Strobe Procedure; MRI Guided Intensity Modulated Radiotherapy (IMRT) Planning; Standard-of-Care Intensity Modulated Radiotherapy (IMRT) Planning; Intensity Modulated Radiotherapy (IMRT)
- Arms
- MRI Guided Intensity Modulated Radiotherapy (IMRT) · Experimental
- Standard-of-Care Intensity Modulated Radiotherapy (IMRT) · Active comparator
- Enrollment
- 90
- Primary outcomes
- Locoregional Control
- Composite Dysphagia Outcome Determined by PEG Tube Dependence at Last Follow-Up
- Composite Dysphagia Outcome Determined by Trace or Frank Aspiration Seen on Modified Barium Swallow Study
- Composite Dysphagia Outcome Determined by Diagnosis of Aspiration Pneumonia
- Composite Dysphagia Outcome Determined by Presence of Pharyngoesophageal Structure on Modified Barium Swallow Study
- Composite Dysphagia Outcome Determined by Presence of Pharyngoesophageal Structure on Endoscopy with Subsequent Need for Dilation
- Sponsor
- M.D. Anderson Cancer Center with National Cancer Institute (NCI)
- Start
- Jan 17, 2018
- Primary completion
- Dec 31, 2026 (estimated)
- Results posted
- No
- Registry record
- NCT03224000 · updated Jun 11, 2026
Publications
linked from the registry- Bahig H, Yuan Y, Mohamed ASR, Brock KK, Ng SP, Wang J, Ding Y, Hutcheson K, McCulloch M, Balter PA, Lai SY, Al-Mamgani A, Sonke JJ, van der Heide UA, Nutting C, Li XA, Robbins J, Awan M, Karam I, Newbold K, Harrington K, Oelfke U, Bhide S, Philippens MEP, Terhaard CHJ, McPartlin AJ, Blanchard P, Garden AS, Rosenthal DI, Gunn GB, Phan J, Cazoulat G, Aristophanous M, McSpadden KK, Garcia JA, van den Berg CAT, Raaijmakers CPJ, Kerkmeijer L, Doornaert P, Blinde S, Frank SJ, Fuller CD. Magnetic Resonance-based Response Assessment and Dose Adaptation in Human Papilloma Virus Positive Tumors of the Oropharynx treated with Radiotherapy (MR-ADAPTOR): An R-IDEAL stage 2a-2b/Bayesian phase II trial. Clin Transl Radiat Oncol. 2018 Aug 24;13:19-23. doi: 10.1016/j.ctro.2018.08.003. eCollection 2018 Nov. PubMed 30386824