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Clinical trial · no report yet · Phase 2

NCT03612154

Study of Lorlatinib in ROS1 Rearranged NSCLC

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads2

The trial

ClinicalTrials.gov
Official title
A Phase II Study of Lorlatnib in ROS1 Rearranged Advanced NSCLC
Phase
Phase 2
Status
Unknown
Conditions
Nonsmall Cell Lung Cancer
Interventions
Lorlatinib
Arms
  • Lorlatinib · Experimental
Enrollment
35 (estimated)
Primary outcomes
  • ORR
Sponsor
National Cancer Center, Korea
Start
May 2, 2019
Primary completion
Dec 31, 2022 (estimated)
Results posted
No
Registry record
NCT03612154 · updated Apr 6, 2022

Publications

linked from the registry
  • Ahn BC, Kim YJ, Lee Y, Suh KJ, Kim SH, Kim DW, Kim TM, Lee KH, Han JY. Lorlatinib in Tyrosine Kinase Inhibitor-Naive Advanced ROS1-Positive Non-Small Cell Lung Cancer: A Phase 2 Nonrandomized Clinical Trial. JAMA Oncol. 2026 Jan 1;12(1):84-89. doi: 10.1001/jamaoncol.2025.5097. PubMed 41296331