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Clinical trial · no report yet · Phase 3

NCT05236946

Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT

  • NCT05236946 ↗
  • Recruiting
  • Tata Memorial Hospital
  • 3 commentary sources found
  • Focused

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built. Commentary is thin so far, so the report would be short.

ChannelFound
X threads3

The trial

ClinicalTrials.gov
Official title
Observation or Upfront Cranial RT in Oncogene Driver Mutated NSCLC With Asymptomatic Brain Metastases: A Phase III Randomized Controlled Trial
Phase
Phase 3
Status
Recruiting
Conditions
Asymptomatic Brain Metastases; Driver Mutation Positive Non-small Cell Lung Cancer
Interventions
Stereotactic radiosurgery/whole brain radiotherapy; Tyrosine kinase inhibitor
Arms
  • Upfront Cranial Radiotherapy · Active comparator
  • Observation (Delayed Cranial Radiotherapy) · Experimental
Enrollment
190 (estimated)
Primary outcomes
  • Intracranial progression free survival at 24 months
Sponsor
Tata Memorial Hospital
Start
Nov 10, 2020
Primary completion
Dec 2025 (estimated)
Results posted
No
Registry record
NCT05236946 · updated Sep 10, 2025