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Clinical trial · no report yet · Phase 2

NCT05630183

A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
Bluesky threads3
Podcasts2
X threads2

The trial

ClinicalTrials.gov
Official title
A Randomized, Open-Label, Phase II Trial of Nab-paclitaxel + Gemcitabine With or Without Botensilimab (AGEN1181) in Patients With Metastatic Pancreatic Cancer Who Have Progressed on Prior 5FU + Leucovorin + Irinotecan + Oxaliplatin (FOLFIRINOX)
Phase
Phase 2
Status
Completed
Conditions
Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
Botensilimab; Gemcitabine; Nab-paclitaxel
Arms
  • Part 1: Combination (Safety Lead-in Phase) · Experimental
  • Part 2: Combination · Experimental
  • Part 2: Standard of Care · Active comparator
Enrollment
81
Primary outcomes
  • Progression-free Survival as Assessed by Investigator
Sponsor
Agenus Inc.
Start
Mar 27, 2023
Primary completion
Jan 5, 2026
Results posted
No
Registry record
NCT05630183 · updated Jun 11, 2026