Clinical trial · no report yet · Phase 1
NCT05707273
CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission
- NCT05707273 ↗
- Active, not recruiting
- City of Hope Medical Center
- Focused
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Preliminary discovery
Commentary in our index that names this trial so far
Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.
| Channel | Found | |
|---|---|---|
| Bluesky threads | 2 | |
| X threads | 1 |
The trial
ClinicalTrials.gov- Official title
- A Pilot Study of CD19-Specific Car T Cells as Consolidation for Older Adults With Acute Lymphoblastic Leukemia in First Remission
- Phase
- Phase 1
- Status
- Active, not recruiting
- Conditions
- B Acute Lymphoblastic Leukemia
- Interventions
- Autologous Anti-CD19 CAR-expressing T Lymphocytes; Biospecimen Collection; Bone Marrow Aspiration and Biopsy; Cyclophosphamide; Fludarabine; Leukapheresis; Questionnaire Administration
- Arms
- Treatment (CD19-CAR T cells) · Experimental
- Enrollment
- 18
- Primary outcomes
- Incidence of dose-limiting toxicity (DLT)
- Incidence of adverse events
- Sponsor
- City of Hope Medical Center with National Cancer Institute (NCI)
- Start
- Apr 26, 2023
- Primary completion
- Sep 21, 2027 (estimated)
- Results posted
- No
- Registry record
- NCT05707273 · updated Oct 8, 2026
Publications
linked from the registry- Aldoss I, Goldberg L, Zhang J, Artz AS, Clark MC, Guan M, Espinosa R, Abimannan T, Wu J, Garcia B, Haas ER, Pathak KV, Lovell B, Pirrotte P, Agrawal V, Sanani N, Kasten S, Tilakawardane D, Wagner JR, Paul J, Shan H, Khaled S, Budde LE, Koller PB, Stein AS, Pullarkat VA, Salhotra A, Aribi A, Marcucci G, Wang X, Forman SJ. CAR T Cell Therapy as a Definitive Consolidation for Older Adults with B-ALL in First Complete Remission. Blood Adv. 2026 Jun 24:bloodadvances.2026020963. doi: 10.1182/bloodadvances.2026020963. Online ahead of print. PubMed 42341322