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Clinical trial · no report yet · Phase 2
NCT06985147
A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)
- NCT06985147 ↗
- Active, not recruiting
- Disc Medicine, Inc
- Focused
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Preliminary discovery
Commentary in our index that names this trial so far
Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.
| Channel | Found | |
|---|---|---|
| X threads | 3 | |
| YouTube | 1 |
The trial
ClinicalTrials.gov- Official title
- A Phase 2, Open-Label Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DISC-3405 in Participants With Polycythemia Vera (PV)
- Phase
- Phase 2
- Status
- Active, not recruiting
- Conditions
- Polycythemia Vera (PV)
- Interventions
- DISC-3405
- Arms
- Within-participant dose escalation · Experimental
- Enrollment
- 60 (estimated)
- Primary outcomes
- Number of participants with treatment-related adverse events as assessed by CTCAE
- Incidence of clinically abnormal vital signs
- Incidence of clinically abnormal physical exam
- Incidence of clinically abnormal electrocardiograms
- Incidence of abnormal laboratory test results
- Sponsor
- Disc Medicine, Inc
- Start
- Aug 12, 2025
- Primary completion
- Feb 2027 (estimated)
- Results posted
- No
- Registry record
- NCT06985147 · updated Jul 31, 2026