Clinical trial · no report yet · Phase 2
NECTORS
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.
- NCT04277858 ↗
- Unknown
- Nader Sadeghi
- Focused
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Preliminary discovery
Commentary in our index that names this trial so far
Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.
| Channel | Found | |
|---|---|---|
| X threads | 2 | |
| Bluesky threads | 1 |
The trial
ClinicalTrials.gov- Official title
- Phase II Study: Induction Chemotherapy Followed by Transoral Robotic Surgery and Neck Dissection for Definitive Management of Oropharyngeal Squamous Cell Carcinoma. (NECTORS Trial)
- Phase
- Phase 2
- Status
- Unknown
- Conditions
- Oropharynx Cancer; Tonsil Cancer; Throat Cancer; Base of the Tongue Carcinoma
- Interventions
- Docetaxel
- Arms
- Neoadjuvant chemotherapy and surgery · Experimental
- Enrollment
- 60 (estimated)
- Primary outcomes
- Primary outcome: progression free survival.
- Sponsor
- Nader Sadeghi with McGill University Health Centre/Research Institute of the McGill University Health Centre
- Start
- Aug 14, 2018
- Primary completion
- Aug 30, 2024 (estimated)
- Results posted
- No
- Registry record
- NCT04277858 · updated Oct 23, 2023
Publications
linked from the registry- Sadeghi N, Mascarella MA, Khalife S, Ramanakumar AV, Richardson K, Joshi AS, Taheri R, Fuson A, Bouganim N, Siegel R. Neoadjuvant chemotherapy followed by surgery for HPV-associated locoregionally advanced oropharynx cancer. Head Neck. 2020 Aug;42(8):2145-2154. doi: 10.1002/hed.26147. Epub 2020 Mar 25. PubMed 32212296
- Sadeghi N, Khalife S, Mascarella MA, Ramanakumar AV, Richardson K, Joshi AS, Bouganim N, Taheri R, Fuson A, Siegel R. Pathologic response to neoadjuvant chemotherapy in HPV-associated oropharynx cancer. Head Neck. 2020 Mar;42(3):417-425. doi: 10.1002/hed.26022. Epub 2019 Nov 27. PubMed 31773857
- Sadeghi N, Li NW, Taheri MR, Easley S, Siegel RS. Neoadjuvant chemotherapy and transoral surgery as a definitive treatment for oropharyngeal cancer: A feasible novel approach. Head Neck. 2016 Dec;38(12):1837-1846. doi: 10.1002/hed.24526. Epub 2016 Jun 14. PubMed 27299983
- Sadeghi N, Subramaniam T, Richardson K, Mascarella M, Zeitouni A, Shenouda G, Sultanem K, Mlynarek A, Caglar D, Esfahani K, Joshi A, Siegel R, Goodman J, Thakkar P, Lee E, Golabi N, Ramanakumar AV, Hier M, Bouganim N. Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Human Papillomavirus-Related Oropharyngeal Cancer. JAMA Otolaryngol Head Neck Surg. 2025 Feb 1;151(2):128-134. doi: 10.1001/jamaoto.2024.3303. PubMed 39636629