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Clinical trial · no report yet · Phase 2

NEOpredict

Neoadjuvant Nivolumab Combination Treatment in Resectable Non-small Cell Lung Cancer Patients

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads5
Podcasts1

The trial

ClinicalTrials.gov
Official title
Neoadjuvant Nivolumab Combination Treatment in Resectable Non-small Cell Lung Cancer Patients: Defining Optimal Combinations and Determinants of Immunological Response
Phase
Phase 2
Status
Completed
Conditions
NSCLC Stage II; NSCLC, Stage IIIA; NSCLC, Stage I
Interventions
Nivolumab 10 MG/ML Intravenous Solution; Relatlimab 10 MG/ML Intravenous Solution
Arms
  • Nivolumab · Experimental
  • Nivolumab/Relatlimab (80 mg) · Experimental
  • Nivolumab/Relatlimab (240 mg) · Experimental
Enrollment
90
Primary outcomes
  • Feasibility of four weeks of preoperative immunotherapy with Nivolumab, Nivolumab plus Relatlimab (80 mg), and Nivolumab plus Relatlimab (240 mg)
Sponsor
University Hospital, Essen
Start
Mar 4, 2020
Primary completion
Nov 27, 2025
Results posted
No
Registry record
NCT04205552 · updated Jun 11, 2026

Publications

linked from the registry
  • Schuler M, Cuppens K, Plones T, Wiesweg M, Du Pont B, Hegedus B, Koster J, Mairinger F, Darwiche K, Paschen A, Maes B, Vanbockrijck M, Lahnemann D, Zhao F, Hautzel H, Theegarten D, Hartemink K, Reis H, Baas P, Schramm A, Aigner C. Neoadjuvant nivolumab with or without relatlimab in resectable non-small-cell lung cancer: a randomized phase 2 trial. Nat Med. 2024 Jun;30(6):1602-1611. doi: 10.1038/s41591-024-02965-0. Epub 2024 Apr 30. PubMed 38689060