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Clinical trial · no report yet · Phase 3

PACIFIC-5

A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients

  • NCT03706690 ↗
  • Active not recruiting
  • AstraZeneca
  • 10 commentary sources found
  • Focused

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
Podcasts4
X threads4
YouTube2

The trial

ClinicalTrials.gov
Official title
A Phase III, Randomised,Double-Blind,Placebo-Controlled,Study of Durvalumab as Consolidation Therapy in Patients With Locally Advanced,Unresectable NSCLC, Who Have Not Progressed Following Definitive, Platinum-Based Chemoradiation Therapy
Phase
Phase 3
Status
Active not recruiting
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
Durvalumab; Placebo
Arms
  • Durvalumab Therapy · Experimental
  • Placebo Therapy · Placebo comparator
Enrollment
407
Primary outcomes
  • Progression-Free Survival (PFS) (Modified Intent-to-Treat [mITT] Set)
Sponsor
AstraZeneca
Start
Nov 27, 2018
Primary completion
Jun 23, 2024
Results posted
Yes
Registry record
NCT03706690 · updated Aug 6, 2026

Publications

linked from the registry
  • Wu YL, Wu L, Bi N, Cil T, Ge H, Zhu Z, Wang CL, Zhang W, Lv D, Mingyan E, Sun J, Pan Y, Krzakowski M, Dikilitas M, Sendur MAN, Kim YC, Yang Y, Mao R, Zhang B, Wang L. PACIFIC-5: a phase III clinical trial of consolidation durvalumab in patients with unresectable stage III NSCLC and no progression after concurrent or sequential chemoradiotherapy. J Hematol Oncol. 2025 Dec 7;18(1):111. doi: 10.1186/s13045-025-01768-1. PubMed 41354932