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Clinical trial · no report yet · Phase 2

PACIFIC 6

A Study to Determine Safety of Durvalumab After Sequential Chemo Radiation in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads20
Podcasts10
YouTube6

The trial

ClinicalTrials.gov
Official title
A Phase II, Open-Label, Multi-Centre, International Safety Study of Durvalumab Following Sequential Chemotherapy and Radiation Therapy in Patients With Stage III, Unresectable Non-Small Cell Lung Cancer (PACIFIC 6)
Phase
Phase 2
Status
Completed
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
Durvalumab
Arms
  • WHO/ECOG PS 0 to 1 Cohort · Experimental
  • WHO/ECOG PS 2 Cohort · Experimental
Enrollment
117
Primary outcomes
  • Number of Patients With Grade 3 and Grade 4 Treatment-related Adverse Events (TRAEs)
Sponsor
AstraZeneca
Start
Apr 16, 2019
Primary completion
Dec 13, 2022
Results posted
Yes
Registry record
NCT03693300 · updated Jun 18, 2024

Publications

linked from the registry
  • Garassino MC, Mazieres J, Reck M, Chouaid C, Bischoff H, Reinmuth N, Cove-Smith L, Mansy T, Cortinovis D, Migliorino MR, Delmonte A, Sanchez JG, Chara Velarde LE, Bernabe R, Paz-Ares L, Perez ID, Trunova N, Foroutanpour K, Faivre-Finn C. Durvalumab After Sequential Chemoradiotherapy in Stage III, Unresectable NSCLC: The Phase 2 PACIFIC-6 Trial. J Thorac Oncol. 2022 Dec;17(12):1415-1427. doi: 10.1016/j.jtho.2022.07.1148. Epub 2022 Aug 9. PubMed 35961520