PRIMALung
PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)
- NCT04790253 ↗
- Recruiting
- European Organisation for Research and Treatment of Cancer - EORTC
- Deep
We haven't built an HCP commentary report on PRIMALung (small-cell lung cancer; tests no drug) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Questions raised in the commentary
Automated from the 38 newest of 45 indexed sources (Jul 2022 – Oct 2026). Each question is raised in at least two. Not an Erudio report: no source links. Not medical advice.
- Whether PCI remains beneficial in the immunotherapy era
- Whether MRI surveillance alone can replace PCI
- How PCI and MRI surveillance compare on survival, cognition, and quality of life
Also discussed: trial recruitment.
Indexed commentary on PRIMALung so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 34 | |
| Podcasts | 7 | |
| YouTube | 4 |
The trial
ClinicalTrials.gov- Official title
- PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)
- Phase
- Phase not applicable
- Status
- Recruiting
- Conditions
- Limited Stage Small Cell Lung Cancer; Extensive-stage Small-cell Lung Cancer
- Interventions
- Prophylactic cranial irradiation
- Arms
- PCI followed by brain MR surveillance · Active comparator
- MRI Active Surveillance · No intervention
- Enrollment
- 600 (estimated)
- Primary outcomes
- Overall survival
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC with UNICANCER
- Start
- Oct 27, 2022
- Primary completion
- Apr 2028 (estimated)
- Results posted
- No
- Registry record
- NCT04790253 · updated Oct 16, 2026