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Clinical trial · no report yet · Phase 1/Phase 2

PRIMAVERA

AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
YouTube2
X threads1

The trial

ClinicalTrials.gov
Official title
A Modular Phase I/II, Open-label, Multicentre Study to Evaluate the Safety, Tolerability, and Efficacy of AZD3470, a PRMT5 Inhibitor, as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies
Phase
Phase 1/Phase 2
Status
Recruiting
Conditions
Lymphoma; Non-Hodgkin Lymphoma; Hodgkin Lymphoma; Peripheral T-cell Lymphoma (PTCL); PTCL-NOS; ALCL; AITL
Interventions
AZD3470; Pembrolizumab
Arms
  • AZD3470 Monotherapy · Experimental
  • AZD3470 in combination with Pembrolizumab · Experimental
Enrollment
161 (estimated)
Primary outcomes
  • Incidence and severity of adverse events (AEs) and serious adverse events (SAEs)
  • Incidence of DLTs (Dose Escalation Cohorts only)
Sponsor
AstraZeneca
Start
Jan 23, 2024
Primary completion
May 3, 2029 (estimated)
Results posted
No
Registry record
NCT06137144 · updated Oct 13, 2026