Clinical trial · no report yet · Phase 2/Phase 3
TOPGEAR
Trial of Preoperative Therapy for Gastric and Esophagogastric Junction Adenocarcinoma
- NCT01924819 ↗
- Active not recruiting
- Australasian Gastro-Intestinal Trials Group
- 93 commentary sources found
- Deep
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Commentary we found
Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.
| Channel | Found | |
|---|---|---|
| X threads | 59 | |
| Podcasts | 19 | |
| YouTube | 15 |
The trial
ClinicalTrials.gov- Official title
- A Randomised Phase II/III Trial of Preoperative Chemoradiotherapy Versus Preoperative Chemotherapy for Resectable Gastric Cancer
- Phase
- Phase 2/Phase 3
- Status
- Active not recruiting
- Conditions
- Gastric Cancer
- Interventions
- Epirubicin + cisplatin + 5-fluorouracil OR epirubicin + cisplatin + capecitabine OR epirubicin + oxaliplatin + capecitabine OR 5-Fluorouracil + leucovorin + oxaliplatin + docetaxel; Preoperative chemoradiotherapy; Gastric resection
- Arms
- Preoperative chemoradiotherapy · Experimental
- Preoperative chemotherapy · Active comparator
- Enrollment
- 574
- Primary outcomes
- Overall survival
- Sponsor
- Australasian Gastro-Intestinal Trials Group with National Health and Medical Research Council, Australia, Trans Tasman Radiation Oncology Group, European Organisation for Research and Treatment of Cancer - EORTC, NCIC Clinical Trials Group
- Start
- Sep 2009
- Primary completion
- Dec 31, 2026 (estimated)
- Results posted
- No
- Registry record
- NCT01924819 · updated Mar 4, 2025
Publications
linked from the registry- Leong T, Smithers BM, Michael M, Haustermans K, Wong R, Gebski V, O'Connell RL, Zalcberg J, Boussioutas A, Findlay M, Willis D, Moore A, Murray WK, Lordick F, O'Callaghan C, Swallow C, Darling G, Miller D, Strickland A, Liberman M, Mineur L, Simes J; Australasian Gastro-Intestinal Trials Group, National Health and Medical Research Council Clinical Trials Centre, Trans-Tasman Radiation Oncology Group, European Organisation for Research and Treatment of Cancer, and Canadian Cancer Trials Group. Preoperative Chemoradiotherapy for Resectable Gastric Cancer. N Engl J Med. 2024 Nov 14;391(19):1810-1821. doi: 10.1056/NEJMoa2405195. Epub 2024 Sep 14. PubMed 39282905