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Clinical trial · no report yet · Phase 3
ROSEL trial: what clinicians have said so far
Trial of Either Surgery or Stereotactic Radiotherapy for Early Stage (IA) Lung Cancer
- NCT00687986 ↗
- Terminated
- Amsterdam UMC, location VUmc
- Deep size, estimated: 301+ verified statements
We haven't built an HCP commentary report on ROSEL (stage IA NSCLC; tests a strategy, not a drug) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on ROSEL so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Indexed so far | |
|---|---|
| 41 posts on X | |
| 1 podcast episode |
The trial
ClinicalTrials.gov- Official title
- A Randomized Clinical Trial of Surgery Versus Radiosurgery (Stereotactic Radiotherapy) in Patients With Stage IA NSCLC Who Are Fit to Undergo Primary Resection
- Phase
- Phase 3
- Status
- Terminated
- Conditions
- Lung Cancer
- Interventions
- stereotactic radiotherapy; primary surgery
- Arms
- primary surgery · Active comparator
- stereotactic radiotherapy · Experimental
- Enrollment
- 22
- Primary outcomes
- local and regional control
- Sponsor
- Amsterdam UMC, location VUmc with ZonMw: The Netherlands Organisation for Health Research and Development
- Start
- Oct 2008
- Primary completion
- Feb 2010
- Results posted
- No
- Registry record
- NCT00687986 · updated Mar 17, 2022
Publications
linked from the registry- Haasbeek CJ, Senan S, Smit EF, Paul MA, Slotman BJ, Lagerwaard FJ. Critical review of nonsurgical treatment options for stage I non-small cell lung cancer. Oncologist. 2008 Mar;13(3):309-19. doi: 10.1634/theoncologist.2007-0195. PubMed 18378542
- Hurkmans CW, Cuijpers JP, Lagerwaard FJ, Widder J, van der Heide UA, Schuring D, Senan S. Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study. Radiat Oncol. 2009 Jan 12;4:1. doi: 10.1186/1748-717X-4-1. PubMed 19138400
- Chang JY, Senan S, Paul MA, Mehran RJ, Louie AV, Balter P, Groen HJ, McRae SE, Widder J, Feng L, van den Borne BE, Munsell MF, Hurkmans C, Berry DA, van Werkhoven E, Kresl JJ, Dingemans AM, Dawood O, Haasbeek CJ, Carpenter LS, De Jaeger K, Komaki R, Slotman BJ, Smit EF, Roth JA. Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials. Lancet Oncol. 2015 Jun;16(6):630-7. doi: 10.1016/S1470-2045(15)70168-3. Epub 2015 May 13. PubMed 25981812
- Louie AV, van Werkhoven E, Chen H, Smit EF, Paul MA, Widder J, Groen HJ, van den Borne BE, De Jaeger K, Slotman BJ, Senan S. Patient reported outcomes following stereotactic ablative radiotherapy or surgery for stage IA non-small-cell lung cancer: Results from the ROSEL multicenter randomized trial. Radiother Oncol. 2015 Oct;117(1):44-8. doi: 10.1016/j.radonc.2015.08.011. PubMed 26492839
- Park S, Kim HJ, Park IK, Kim YT, Kang CH. Stereotactic ablative radiotherapy versus surgery in older patients with stage I lung cancer. Eur J Cardiothorac Surg. 2021 Jul 14;60(1):74-80. doi: 10.1093/ejcts/ezab045. PubMed 33668061