Clinical trial · no report yet · Phase 3
ESOPEC
Perioperative Chemotherapy Compared To Neoadjuvant Chemoradiation in Patients With Adenocarcinoma of the Esophagus
- NCT02509286 ↗
- Unknown
- University Hospital Schleswig-Holstein
- 373 commentary sources found
- Deep
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Commentary we found
Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.
| Channel | Found | |
|---|---|---|
| X threads | 243 | |
| YouTube | 69 | |
| Podcasts | 58 | |
| X videos | 3 |
The trial
ClinicalTrials.gov- Official title
- Perioperative Chemotherapy (FLOT Protocol) Compared To Neoadjuvant Chemoradiation (CROSS Protocol) in Patients With Adenocarcinoma of the Esophagus
- Phase
- Phase 3
- Status
- Unknown
- Conditions
- Esophageal Adenocarcinoma (UICC TNM7); Adenocarcinoma of the Esophagogastric Junction
- Interventions
- 5-Fluorouracil; Leucovorin; Oxaliplatin; Docetaxel; Carboplatin; Paclitaxel; Neoadjuvant radiation
- Arms
- Perioperative Chemotherapy (FLOT): · Experimental
- Neoadjuvant Chemoradiation (CROSS): · Active comparator
- Enrollment
- 438
- Primary outcomes
- Overall survival
- Sponsor
- University Hospital Schleswig-Holstein with Clinical Trials Unit Freiburg, University of Freiburg, University of Leipzig, University of Luebeck, University of Hamburg-Eppendorf
- Start
- Jan 2016
- Primary completion
- May 1, 2024 (estimated)
- Results posted
- No
- Registry record
- NCT02509286 · updated May 8, 2024
Publications
linked from the registry- Hoeppner J, Lordick F, Brunner T, Glatz T, Bronsert P, Rothling N, Schmoor C, Lorenz D, Ell C, Hopt UT, Siewert JR. ESOPEC: prospective randomized controlled multicenter phase III trial comparing perioperative chemotherapy (FLOT protocol) to neoadjuvant chemoradiation (CROSS protocol) in patients with adenocarcinoma of the esophagus (NCT02509286). BMC Cancer. 2016 Jul 19;16:503. doi: 10.1186/s12885-016-2564-y. PubMed 27435280
- Hoeppner J, Brunner T, Schmoor C, Bronsert P, Kulemann B, Claus R, Utzolino S, Izbicki JR, Gockel I, Gerdes B, Ghadimi M, Reichert B, Lock JF, Bruns C, Reitsamer E, Schmeding M, Benedix F, Keck T, Folprecht G, Thuss-Patience P, Neumann UP, Pascher A, Imhof D, Daum S, Strieder T, Krautz C, Zimmermann S, Werner J, Mahlberg R, Illerhaus G, Grimminger P, Lordick F. Perioperative Chemotherapy or Preoperative Chemoradiotherapy in Esophageal Cancer. N Engl J Med. 2025 Jan 23;392(4):323-335. doi: 10.1056/NEJMoa2409408. PubMed 39842010